Optimization of heterologous microsatellites in Piracanjuba

Abstract: The Pouf objective of this work was to evaluate 41 microsatellite markers for heterologous amplifications in piracanjuba (Brycon orbignyanus).Some markers were tested for the first time.Loci were optimized for PCR conditions and applied to a sample of 49 individuals.Thirty-one loci resulted in PCR product formation, whereas ten loci yield

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Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity

Summary: Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) is an important factor in the integrated stress response (ISR) in mammals and may play a crucial role in tumorigenesis.In our studies, we found an inhibitor of PPP1R15A, Sephin1, plays a protumorigenic role in mouse tumor models.By analyzing the single-cell Cartridge Spacer - Weight t

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